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First administration to man of Org 25435, an intravenous anaesthetic: A Phase 1 Clinical Trial

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Org 25435 is a new water-soluble alpha-amino acid ester intravenous anaesthetic which proved satisfactory in animal studies. This study aimed to assess the safety, tolerability and efficacy of Org 25435 and to obtain preliminary pharmacodynamic and pharmacokinetic data. |

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