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Báo cáo y học: "Cartilage markers and their association with cartilage loss on magnetic resonance imaging in knee osteoarthritis: the Boston Osteoarthritis Knee Study"

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Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học General Psychiatry cung cấp cho các bạn kiến thức về ngành y đề tài: Cartilage markers and their association with cartilage loss on magnetic resonance imaging in knee osteoarthritis: the Boston Osteoarthritis Knee Study. | Available online http arthritis-research.eom content 9 5 R108 Research article Cartilage markers and their association with cartilage loss on magnetic resonance imaging in knee osteoarthritis the Boston Osteoarthritis Knee Study David J Hunter1 Jiang Li1 Michael LaValley1 Doug C Bauer2 Michael Nevitt2 Jeroen DeGroot3 Robin Poole4 David Eyre5 Ali Guermazi1 Dan Gale6 and David T Felson1 Clinical Epidemiology Research and Training Unit Boston University School of Medicine Boston MA USA 2University of California San Francisco San Francisco CA 94107 USA 3Immunological and Infectious Diseases Division TNO Quality of Life Leiden The Netherlands 4McGill University Montreal QC Canada 5Department of Orthopaedics and Sports Medicine University of Washington Seattle WA 98195 USA 6VirtualScopics Rochester NY 14625 USA Corresponding author David J Hunter djhunter@bu.edu Received 4 Apr 2007 Revisions requested 23 May 2007 Revisions received 12 Sep 2007 Accepted 24 Oct 2007 Published 24 Oct 2007 Arthritis Research Therapy 2007 9 R108 doi 10.1186 ar2314 This article is online at http arthritis-research.com content 9 5 R108 2007 Hunter et al. licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License http creativecommons.org licenses by 2.0 which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Open Access Abstract We used data from a longitudinal observation study to determine whether markers of cartilage turnover could serve as predictors of cartilage loss on magnetic resonance imaging MRI . We conducted a study of data from the Boston Osteoarthritis of the Knee Study BOKS a completed natural history study of knee osteoarthritis OA . All subjects in the study met American College of Rheumatology criteria for knee OA. Baseline and follow-up knee magnetic resonance images were scored for cartilage loss by means of the WORMS Whole Organ Magnetic .

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