Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: An unusual case of autoimmune pancreatitis presenting as pancreatic mass and obstructive jaundice: a case report and review of the literature. | Efeovbokhan et al. Journal of Medical Case Reports 2011 5 253 http content 5 1 253 JOURNALOF medical Ur Case REPORTS CASE REPORT Open Access An unusual case of autoimmune pancreatitis presenting as pancreatic mass and obstructive jaundice a case report and review of the literature Nephertiti Efeovbokhan1 Ashima Makol1 Reuben V Cuison2 Rebecca M Minter3 Veera-Pavan Kotaru1 Barbara A Conley4 and Sreenivasa R Chandana5 Abstract Background Autoimmune pancreatitis is a rare chronic inflammatory pancreatic disease that is increasingly being diagnosed worldwide. As a result of overlap in clinical and radiological features it is often misdiagnosed as pancreatic cancer. We report the case of a patient with autoimmune pancreatitis that was initially misdiagnosed as pancreatic cancer. Case presentation A 31-year-old Caucasian man presented to our hospital with epigastric pain jaundice and weight loss. His CA 19-9 level was elevated and computed tomography and endoscopic ultrasound revealed a pancreatic head mass abutting the portal vein. Endoscopic retrograde cholangiopancreaticography showed narrowing of the biliary duct and poor visualization of the pancreatic duct. Fine-needle aspiration biopsy revealed atypical ductal epithelial cells which raised clinical suspicion of adenocarcinoma. Because of the patient s unusual age for the onset of pancreatic cancer and the acuity of his symptoms he was referred to a tertiary care center for further evaluation. His immunoglobulin G4 antibody level was 365 mg dL and repeat computed tomography showed features typical of autoimmune pancreatitis. The patient s symptoms resolved with corticosteroid therapy. Conclusion Autoimmune pancreatitis is a rare disease with an excellent response to corticosteroid therapy. Its unique histological appearance and response to corticosteroid therapy can reduce unnecessary surgical procedures. A thorough evaluation by a multidisciplinary team is important in rendering the .