Pesticide profiles : Toxicity, environmental impact and fate - Chapter 10

Các thuốc trừ sâu 10,1 Chương tổng quan Các thành phần thuốc trừ sâu hoạt động bao phủ trong chương này đại diện cho một mảng rộng của các hợp chất mà không cho vay mình để phân loại dễ dàng. Do đó tổ chức theo sử dụng của họ, có nghĩa là, thuốc diệt nấm, thuốc diệt cỏ, thuốc trừ sâu, và những người khác. | chapter ten Other pesticides Chapter overview The pesticide active ingredients covered in this chapter represent a wide array of compounds that do not lend themselves to easy classification. They are therefore organized according to their use that is fungicides herbicides insecticides and others. Fungicides Benomyl Figure Benomyl. Trade or other names Commercial names for products containing benomyl include Agrocit Benex Benlate Benosan Fundazol Fungidice 1991 and Tersan 1991. Benomyl is compatible with many other pesticides. Regulatory status Benomyl is a General Use Pesticide GUP . The EPA categorizes it as toxicity class IV practically nontoxic. Benomyl-containing products carry the Signal Word CAUTION. Introduction Benomyl is a systemic benzimidazole fungicide that is selectively toxic to microorganisms and to invertebrates especially earthworms. It is used against a wide range of fungal diseases of field crops fruits nuts ornamentals mushrooms and 2000 CRC Press LLC turf. Formulations include wettable powder dry flowable powder and dispersible granules. Toxicological effects Acute toxicity Benomyl is of such a low acute toxicity to mammals that it has been impossible or impractical to administer doses large enough to firmly establish an LD50. Thus the LD50 is greater than 10 000 mg kg in rats and greater than 3400 mg kg in rabbits using a 50 wettable powder formulation . Because of its high LD50 there is a low risk for acute poisoning from this compound 1 . Skin irritation may occur for workers exposed to benomyl. Skin reactions have also been seen in rats and guinea pigs. Most organisms can become sensitized to the compound as well. Benomyl is readily absorbed into the body by inhaling the dust but there are no reports of toxic effects to humans by this route of exposure. The inhalation LC50 in rats is greater than 2 mg L 2 . Chronic toxicity When rats were fed diets containing about 150 mg kg day for 2 years no toxic effects were .

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