Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Diabetic ketoacidosis complicated by the use of ecstasy: a case report. | Gama et al. Journal of Medical Case Reports 2010 4 240 http content 4 1 240 jAg JOURNALOF medical ÌỤr case REPORTS CASE REPORT Open Access Diabetic ketoacidosis complicated by the use of ecstasy a case report Mirnaluci Paulino Ribeiro Gama1 Barbara Vicente de Souza2 Ana Carolina Ossowski3 Rafaela Cristina Perraro4 Abstract Introduction Ecstasy 3 4-methylenedioxymethamphetamin a hallucinogenic amphetamine is often used by young people especially at raves . This illicit drug can cause many metabolic changes and its use when associated with prolonged exercise may exacerbate ketoacidosis in type 1 diabetic patients. Case presentation This is a case of ketoacidosis complicated by the use of ecstasy in a 19-year-old insulindependent diabetic Caucasian woman. Conclusion The use of ecstasy may trigger diabetic ketoacidosis in patients with a preexisting metabolic disorder Introduction A considerable number of young people are exposed to 3 4-methylenedioxymethamphetamine MDMA - also known as ecstasy 1 a synthetic compound with structural and pharmacological characteristics similar to those of amphetamines. The use of this drug has increased considerably over the last 15 years 2 . The drug was originally developed as an appetite suppressant although it was never promoted commercially for that purpose. Given its psycho-affective properties of inducing euphoria disinhibition and sexual arousal the drug was later used as an adjunct to psychotherapy. In the 1980s MDMA became a trendy drug of abuse particularly at rave parties and dance clubs. However its potential for abuse was soon recognized thus prompting government officials to place restrictions on its use 3 . In Brazil the first shipments of ecstasy arrived in São Paulo in 1994 mainly from Amsterdam and began to be trafficked mostly at raves and dance clubs 4 . Ecstasy is mistakenly seen by young people as a safe drug compared with amphetamines. However it not only has some of the toxicity of .