Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Extensive psoriasis induced by pegylated interferon: a case report | Journal of Medical Case Reports BioMed Central Open Access Extensive psoriasis induced by pegylated interferon a case report Vincenzo Citro1 Raffaele Fristachi2 and Giovanni Tarantino 3 Address . of General Medicine Hepatological Unit Mauro Scarlato Hospital Scafati SA Italy . of Pathology Ospedali Riuniti delle Tre Valli ASL SA 1 Nocera Inferiore Italy and 3Department of Clinical and Experimental Medicine Federico II University Medical School of Naples Italy Email Vincenzo Citro - Raffaele Fristachi - re2005@ Giovanni Tarantino - tarantin@ Corresponding author Published 17 September 2007 Received 8 January 2007 - . J . I Accepted 17 September 2007 Journal of Medical Case Reports 2007 1 86 doi l752-l947-l-86 This article is available from http content l l 86 2007 Citro et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract This paper describes the clinical course of a patient with chronic hepatitis C genotype 2a 2c previously treated with Interferon a2b and subsequently with Lymphoblastoid Interferon without any response and also without any cutaneous side effects. The patient a 50 year-old woman was re-treated with Pegylated a2b Interferon plus Ribavirin for 24 weeks at standard doses during the third month of therapy she developed a mild form of psoriasis. However encouraged by the progressive improvement of her transaminase levels and viral load decrease the patient asked to continue the treatment she normalized the transaminase levels during the fourth month and showed HCV-RNA negativity during the fifth month of therapy. Nevertheless the psoriasis become worse extending to over 75 of her body. Therapy was completed after sixth .
