Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Liver and brain abscess caused by Aggregatibacter paraphrophilus in association with a large patent foramen ovale: a case report | Ariyaratnam et al. Journal of Medical Case Reports 2010 4 69 http content 4 1 69 jAc JOURNALOF medical ÌỤr case REPORTS CASE REPORT Open Access Liver and brain abscess caused by Aggregatibacter paraphrophilus in association with a large patent foramen ovale a case report 1 1 112 Shaumya Ariyaratnam Parag R Gajendragadkar Richard J Dickinson Phil Roberts Kathryn Harris Andrew Carmichael3 Johannis A Karas1 4 Abstract Introduction Aggregatibacter paraphrophilus former name Haemophilus paraphrophilus is a normal commensal of the oral flora. It is a rare cause of hepatobiliary or intracerebral abscesses. Case presentation We report a case of a 53-year-old Caucasian man with a liver abscess and subsequent brain abscesses caused by Aggregatibacter paraphrophilus. The probable source of the infection was the oral flora of our patient following ingestion of a dental filling. The presence of a large patent foramen ovale was a predisposing factor for multifocal abscesses. Conclusion In this case report we describe an unusual case of a patient with both liver and brain abscesses caused by an oral commensal Aggregatibacter paraphrophilus that can occasionally show significant pathogenic potential. Introduction Aggregatibacter paraphrophilus former name Haemophilus paraphrophilus is a species of Gram-negative coccobacilli formerly in the genus Haemophilus now Aggregatibacter 1 . It is a normal commensal of the human oral cavity and pharynx. It is documented as being a rare cause of subacute bacterial endocarditis brain abscess sinusitis arthritis and osteomyelitis and is often associated with recent dental treatment 2 . Diagnosis unfortunately is hindered by its fastidious and slow-growing nature 3 . Here we describe a rare case of a patient with both liver and brain abscesses caused by Aggregatibacter paraphrophilus incidentally found to have a patent foramen ovale. Case presentation A 53-year-old Caucasian man presented with a five-day history of .