TTuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài:uberculosis of the breast with erythema nodosum: a case report | Kao et al. Journal of Medical Case Reports 2010 4 124 http content 4 1 124 CASE REPORTS CASE REPORT Open Access Tuberculosis of the breast with erythema nodosum a case report Pao-Tsuan Kao 1 2 May-Yu Tu1 3 Sai-Hung Tang4 and Hon-Kwong Ma 1 3 Abstract Introduction There has been an increasing number of tuberculosis cases worldwide but tuberculosis of the breast remains rare. In rare cases this is seen with a cutaneous manifestation of erythema nodosum. Case presentation We report the case of a 33-year-old Chinese woman with tuberculosis of the left breast accompanied by erythema nodosum on the anterior aspect of both lower legs. Due to her poor clinical response to conventional therapy and the histopathological findings of fine needle aspiration cytology there were strong indications of tuberculosis. Her clinical diagnosis was confirmed by molecular detection of Mycobacterium tuberculosis complex by polymerase chain reaction. The diagnosis was further confirmed by a second polymerase chain reaction test of erythema nodosum which tested positive for Mycobacterium tuberculosis complex. She received antituberculous therapy for 18 months and finally underwent residual lumpectomy. During her follow-up examination after 12 months no evidence of either residual or recurrent disease was present. Conclusion Histopathological features and a high index of clinical suspicion are necessary to confirm a diagnosis of tuberculosis of the breast. Anti-tuberculous therapy with or without simple surgical intervention is the core treatment. Introduction Tuberculosis TB is one of the leading infectious diseases worldwide. Extrapulmonary TB involving the breast is extremely rare. Clinical examination usually fails to differentiate breast TB from breast carcinoma. Vulnerability to breast TB is increased in women who are young married multiparous and who breast-feed 1 . Histopathological examination using fine needle aspiration cytology FNAC .
