Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: A review of the evidence for the effectiveness of primary prevention interventions for Hepatitis C among injecting drug users | Harm Reduction Journal BioMed Central Open Access Review A review of the evidence for the effectiveness of primary prevention interventions for Hepatitis C among injecting drug users Nat MJ Wright 1 2 and Charlotte NE Tompkins2 Address 1Her Majesty s Prison Leeds Leeds UK and 2Leeds West Primary Care Trust Leeds UK Email Nat MJ Wright - Charlotte NE Tompkins - Corresponding author Published 06 September 2006 Received 19 May 2006 __ AA J inli z 7 Accepted 06 September 2006 Harm Reduction Journal 2006 3 27 doi l477-75l7-3-27 This article is available from http content 3 l 27 2006 Wright and Tompkins licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background Hepatitis C HCV prevalence is most common amongst injecting drug users where up to 98 of the population can be infected despite a low prevalence of HIV. This review considers the evidence for the effectiveness of primary prevention interventions to reduce incidence or prevalence of hepatitis C. Methods Systematic review of the major electronic medical databases Medline EMBASE PsycINFO CINAHL and the Cochrane Library Evidence Based Health . Either intervention or observational studies were included if they described an intervention targeting injecting drug using populations with the outcome to reduce either the prevalence or incidence of hepatitis C infection. Results l8 papers were included in the final review from 1007 abstracts. Needle exchange programmes reduce the prevalence of HCV though prevalence remains high. Similarly the effectiveness of methadone maintenance treatment is only marginally effective at reducing HCV incidence. There is limited evidence
