Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Uncoupling GP1 and GP2 expression in the Lassa virus glycoprotein complex: implications for GP1 ectodomain shedding | Virology Journal BioMed Central Research Uncoupling GPI and GP2 expression in the Lassa virus glycoprotein complex implications for GP1 ectodomain shedding Megan M Illick41 Luis M Branco42 Joseph N Fair2 3 4 Kerry A Illick 1 5 Alex Matschiner1 Randal Schoepp6 Robert F Garry 2 and Mary C Guttieri 4 Open Access Address 1BioFactura Inc. Rockville MD USA 2Tulane University Health Sciences Center New Orleans LA USA 3Tulane University School of Public Health Tropical Medicine New Orleans LA USA 4Virology Division United States Army Medical Research Institute of Infectious Diseases Fort Detrick MD USA 5Department of Science Cedar Crest College Allentown PA USA and 6Diagnostic Systems Division United States Army Medical Research Institute of Infectious Diseases Fort Detrick MD USA Email Megan M Illick - millick@ Luis M Branco - lbranco@ Joseph N Fair - fair@ Kerry A Illick - kaillick@ Alex Matschiner - amatschiner@ Randal Schoepp - Robert F Garry - rfgarry@ Mary C Guttieri - marycguttieri@ Corresponding authors fEqual contributors Published 23 December 2008 Received 14 December 2008 Accepted 23 December 2008 Virologyjournal 2008 5 161 doi l743-422X-5-l6l This article is available from http content 5 l l6l 2008 Illick et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background Sera from convalescent Lassa fever patients often contains antibodies to Lassa virus LASV glycoprotein l GPl and glycoprotein 2 GP2 Immunization of non-human primates with viral vectors expressing the arenaviral glycoprotein complex GPC confers full protective immunity against a lethal challenge with .
