Báo cáo sinh học: " Evidence of HIV exposure and transient seroreactivity in archived HIV-negative severe hemophiliac sera"

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành hóa học dành cho các bạn yêu hóa học tham khảo đề tài: Evidence of HIV exposure and transient seroreactivity in archived HIV-negative severe hemophiliac sera | Virology Journal BioMed Central Research Open Access Evidence of HIV exposure and transient seroreactivity in archived HIV-negative severe hemophiliac sera Scott A Tenenbaum 1 Cindy A Morris2 Steve S Alexander3 Harris E McFerrin2 Robert F Garry2 and Cindy A Leissinger4 Address Department of Biomedical Sciences Ge NY Sis Center for Excellence in Cancer Genomics University at Albany-SUNY Albany NY USA 2Microbiology and Immunology Tulane University School of Medicine Tulane University School of Medicine New Orleans LA USA 3Ortho Diagnostic Systems HlV and Hepatitis Research and Development Raritan NJ USA and 4Department of Medicine Section of Hematology and Medical Oncology Tulane University School of Medicine New Orleans LA USA Email Scott ATenenbaum - stenenbaum@ Cindy A Morris - cmorris2@ Steve S Alexander - SAlexand@ Harris E McFerrin - mharris1@ Robert F Garry - rfgarry@ Cindy A Leissinger - cleissi@ Corresponding author Published 17 August 2005 Virology Journal 2005 2 65 doi 1743-422X-2-65 Received 08 August 2005 Accepted 17 August 2005 This article is available from http content 2 1 65 2005 Tenenbaum et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background Approximately 25 of hemophiliacs that were frequently exposed to blood clotting factor concentrates CFCs contaminated with human immunodeficiency virus HIV are presently HIV seronegative. In this study we sought to determine if some of these individuals were at any time transiently HIV seropositive. In the early to mid-1980s the majority of severe hemophilia patients were exposed to CFCs contaminated with HIV. Although many of these hemophiliacs became .

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