Tuyển tập các báo cáo nghiên cứu về hóa học được đăng trên tạp chí sinh học quốc tế đề tài : Histomorphological study of the spinal growth plates from the convex side and the concave side in adolescent idiopathic scoliosis | Journal of Orthopaedic Surgery and Research Research article BioMed Central Open Access Histomorphological study of the spinal growth plates from the convex side and the concave side in adolescent idiopathic scoliosis Shoufeng Wang Yong Qiu Zezhang Zhu Zhaolong Ma Caiwei Xia and Feng Zhu Address Spine Surgery Drum Tower Hospital Nanjing University Medical School Nanjing China Email Shoufeng Wang - wangshoufeng@ Yong Qiu - scoliosis2002@ ZezhangZhu - zhuzezhang@ Zhaolong Ma - njmzlong@ Caiwei Xia - cwsummer@ Feng Zhu - cnspine@ Corresponding author Published II November 2007 Received 26 December 2006 Journal of Orthopaedic Surgery and Research 2007 2 19 doi 1749-799X-2-19 Accepted II November 2007 This article is available from http content 2 I I9 2007 Wang et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Asymmetrical growth of the vertebrae has been implicated as one possible etiologic factor in the pathogenesis of adolescent idiopathic scoliosis. The longitudinal vertebral growth derives from the endochondral ossification of the vertebral growth plate. In the present study the growth plates from the convex and concave side of the vertebrae were characterized by the method of histology and immunohistochemistry to evaluate the growth activity cell proliferation and apoptosis. Normal zoned architectures were observed in the convex side of the growth plate and disorganized architectures in the concave side. The histological grades were significantly different between the convex and the concave side of the growth plate in the apex vertebrae P . The histological difference was also found significant statistically between end .
