Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành hóa học dành cho các bạn yêu hóa học tham khảo đề tài: A comparative study of non-covalent encapsulation methods for organic dyes into silica nanoparticles | Auger et al. Nanoscale Research Letters 2011 6 328 http content 6 1 328 o Nanoscale Research Letters a SpringerOpen Journal NANO EXPRESS Open Access A comparative study of non-covalent encapsulation methods for organic dyes into silica nanoparticles Aurélien Auger Jorice Samuel Olivier Poncelet and Olivier Raccurt Abstract Numerous luminophores may be encapsulated into silica nanoparticles 100 nm using the reverse microemulsion process. Nevertheless the behaviour and effect of such luminescent molecules appear to have been much less studied and may possibly prevent the encapsulation process from occurring. Such nanospheres represent attractive nanoplatforms for the development of biotargeted biocompatible luminescent tracers. Physical and chemical properties of the encapsulated molecules may be affected by the nanomatrix. This study examines the synthesis of different types of dispersed silica nanoparticles the ability of the selected luminophores towards incorporation into the silica matrix of those nanoobjects as well as the photophysical properties of the produced dye-doped silica nanoparticles. The nanoparticles present mean diameters between 40 and 60 nm as shown by TEM analysis. Mainly the photophysical characteristics of the dyes are retained upon their encapsulation into the silica matrix leading to fluorescent silica nanoparticles. This feature article surveys recent research progress on the fabrication strategies of these dye-doped silica nanoparticles. Introduction The development and need for silica-based fluorescent nanoparticles as markers in biological applications such as sensing and imaging have spread significantly since the 1990s 1-3 . Fluorescent labelling of biomolecules has been established as an essential tool in many biological investigations. Recently significant advances have led to a large variety of labelling reagents based on inorganic quantum dots 4 lanthanide-doped oxides 5 6 metallic gold 7 8 or organic .
