Báo cáo hóa học: " Research Article A Principal Component Regression Approach for Estimating Ventricular Repolarization Duration Variability"

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành hóa học dành cho các bạn yêu hóa học tham khảo đề tài: Research Article A Principal Component Regression Approach for Estimating Ventricular Repolarization Duration Variability | Hindawi Publishing Corporation EURASIP Journal on Advances in Signal Processing Volume 2007 Article ID 58358 10 pages doi 2007 58358 Research Article A Principal Component Regression Approach for Estimating Ventricular Repolarization Duration Variability Mika P. Tarvainen 1 Tomi Laitinen 2 Tiina Lyyra-Laitinen 2 Juha-Pekka Niskanen 1 and Pasi A. Karjalainen1 1 Department of Physics University of Kuopio . Box 1627 70211 Kuopio Finland 2 Department of Clinical Physiology and Nuclear Medicine Kuopio University Hospital . Box 1777 70211 Kuopio Finland Received 28 April 2006 Revised 27 September 2006 Accepted 29 October 2006 Recommended by Pablo Laguna Lasaosa Ventricular repolarization duration VRD is affected by heart rate and autonomic control and thus VRD varies in time in a similar way as heart rate. VRD variability is commonly assessed by determining the time differences between successive R- and T-waves that is RT intervals. Traditional methods for RT interval detection necessitate the detection of either T-wave apexes or offsets. In this paper we propose a principal-component-regression- PCR- based method for estimating RT variability. The main benefit of the method is that it does not necessitate T-wave detection. The proposed method is compared with traditional RT interval measures and as a result it is observed to estimate RT variability accurately and to be less sensitive to noise than the traditional methods. As a specific application the method is applied to exercise electrocardiogram ECG recordings. Copyright 2007 Mika P. Tarvainen et al. This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. 1. INTRODUCTION Ventricular repolarization duration VRD is known to be affected by heart rate HR and autonomic control mainly through sympathetic branch and thus VRD varies in time in a similar way .

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