It is possible to anticipate that promising inhibitors of photosynthesis will certainly be found by exploring the natural product pool. From nature, it is also possible that more active compounds with low toxicity and improved selectivity will be found. Promising photosynthetic inhibitors has also been revealed by the synthetic studies. One important challenge in the field of weed management is related to selectivity. In other words, chemicals should exert their action only on weeds. As can be noticed in the discussion of the studies published in the literature during the last years, this issue has not been addressed. Future works should also be concerned with this important matter
