Despite worldwide efforts to assess and control cardiovascular risk factors, cardiac diseases and in particular coronary artery disease (CAD) are still the foremost causes of death in the developed countries of Western Europe, North America and Asia and are becoming increasingly common in Eastern Europe and the developing world (Deanfield 2001). Approximately one in five deaths is currently related to cardiac disease in Europe and the US. Nearly 500,000 deaths caused by CAD are reported every year in the US, over 600,000 in Europe, 170,000 of these in Germany alone. Over 12 million US citizens have a history of CAD, while every year million US and 300,000.
