We investigated the effects on ginseng cell and ginsenoside production when macro element concentrations were manipulated in the culture media. Biomass growth was greatest in the medium supplemented with strength NH4NO3, whereas ginsenoside accumulation was highest ( mg/g DW). At levels of strength KNO3, cell growth was maximum, but strength of KNO3 led to the greatest ginsenoside content ( mg/g DW).