The sequencing of the human genome has generated excitement about the potential of genomic innovations to improve medical care, preventive and community health services, and public health. Until fairly recently, genetic information was used primarily in the diagnosis of relatively rare genetic diseases, such as cystic fibrosis and Huntington’s Disease, but a transformation in the use of genetic and genomic information is under way. Genetic markers of increased risk for such chronic diseases as diabetes and coronary artery disease have been identified. Research on how genes influence the effects of drugs holds promise for helping physicians individualize drug therapy