In contrast, only three percent of women who had a negative HPV DNA test for 13 high risk types developed CIN3+ within the timeframe of the study, indicating that frequent screening of these women may be unnecessary. The researchers found that although infection with some types, such as HPV 53, 56, 59, and 68, were prone to persist for 2 years, they did not lead to lesions during the entire follow-up period. A study in Italy18 investigated the efficacy of HPV DNA testing for CIN and cervical cancers and supported the use of stand-alone HPV DNA testing as.
