Despite the dramatic decline in the number of reported cases of tuberculosis (TB) in New York City, many New Yorkers remain at high risk for developing active tuberculosis disease, once infected with Mycobacterium tuberculosis. Groups at especially high risk include contacts of persons with active tuberculosis, HIV-infected persons, individuals with certain predisposing medical conditions, and recent immigrants from countries with high rates of TB. In April 2000, the American Thoracic Society (ATS) and the Centers for Disease Control and Prevention (CDC) revised their guidelines for the treatment of latent tuberculosis infection (LTBI). The Infectious Diseases Society of America and the American College of Physicians endorsed these guidelines. Sections.
