MINIREVIEW Protein tyrosine phosphatases: dual-specificity phosphatases in health and disease Rafael Pulido1 and Rob Hooft van Huijsduijnen2 ´ ´ 1 Centro de Investigacion Prıncipe Felipe, Valencia, Spain 2 Merck Serono International, Geneva, Switzerland Keywords arthritis; asthma; cancer; laforin; multiple sclerosis; myoclonus epilepsy; myotubular myopathy; protein phosphorylation ⁄ dephosphorylation; PTEN; signal transduction Correspondence ´ ´ R. Pulido, Centro de Investigacion Prıncipe Felipe, Avda Autopista del Saler, 16-3, 46013 Valencia, Spain Fax: +34 96 3289701 Tel: +34 96 3289680 E-mail: rpulido@ R. Hooft, Merck Serono International ., 9, chemin des Mines, 1202 Geneva, Switzerland Fax: +41 224149771 Tel: +41 224149602 E-mail: (Received 27 October 2007,.
