X-ray crystallography of the nonheme manganese catalase fromLactobacillus plantarum(LPC) [Barynin, ., Whit-taker, ., Antonyuk, ., Lamzin, ., Harrison, ., Artymiuk, . & Whittaker, . (2001)Structure9, 725–738] has revealed the structure of the dimanganese redox cluster together with its protein environment. The oxidized [Mn(III)Mn(III)] cluster is bridged by two solvent molecules (oxo and hydroxo, respectively) together with a l1,3bridging glutamate carboxylate and is embedded in a web of hydrogen bonds involving an outer sphere tyrosine residue (Tyr42). .
