The aim of this study was to compare the activity of antioxidant enzymes superoxide dismutase (SOD), catalase (CAT), and total and selenium-dependent glutathione peroxidase (total GSH-Px and Se-GSH-Px) in the liver of wild boars (Sus scrofa) selected from a selenium-deficient area with respect to season of the year, sex, and age. | Turkish Journal of Biology Turk J Biol (2015) 39: 129-138 © TÜBİTAK doi: Research Article Activity of antioxidant enzymes in the liver of wild boars (Sus scrofa) from a selenium-deficient area depending on sex, age, and season of the year 1 2 1, 3 Dorota JANKOWIAK , Renata PILARCZYK , Radosław DROZD *, Bogumiła PILARCZYK , 3 4 5 6 3 Agnieszka TOMZA-MARCINIAK , Gabriela WYSOCKA , Izabella RZĄD , Arleta DROZD , Jarosław KUBA 1 Department of Immunology, Microbiology, and Physiological Chemistry, West Pomeranian University of Technology, Szczecin, Poland 2 Laboratory of Biostatistics, West Pomeranian University of Technology, Szczecin, Poland 3 Department of Animal Reproduction, Biotechnology, and Environmental Hygiene, West Pomeranian University of Technology, Szczecin, Poland 4 Department of Horticulture, Laboratory of Storage and Processing, Faculty of Environmental Studies and Agriculture, West Pomeranian University of Technology, Szczecin, Poland 5 Department of Ecology and Environmental Protection, University of Szczecin, Szczecin, Poland 6 Department of Biochemistry and Human Nutrition, Pomeranian Medical University, Szczecin, Poland Received: Accepted: Published Online: Printed: Abstract: The aim of this study was to compare the activity of antioxidant enzymes superoxide dismutase (SOD), catalase (CAT), and total and selenium-dependent glutathione peroxidase (total GSH-Px and Se-GSH-Px) in the liver of wild boars (Sus scrofa) selected from a selenium-deficient area with respect to season of the year, sex, and age. Only season had a significant effect on liver Se content. Liver selenium concentration in the wild boars was highest in spring ( µg/g wet weight) and lowest in winter ( µg/g wet weight) (P ). SOD activity was highly negatively correlated with selenium concentration in the winter (–; P ). The analysis of correlations