Xây dựng danh mục tương tác thuốc cần chú ý trong thực hành lâm sàng tại Khoa Nội - Bệnh viện Kiến An Hải Phòng

Mục đích của nghiên cứu này nhằm xây dựng danh mục tương tác thuốc cần chú ý trong thực hành lâm sàng tại Khoa Nội, Bệnh viện Kiến An Hải Phòng. | Xây dựng danh mục tương tác thuốc cần chú ý trong thực hành lâm sàng tại Khoa Nội - Bệnh viện Kiến An Hải Phòng VNU Journal of Science: Medical and Pharmaceutical Sciences, Vol. 35, No. 2 (2019) 54-67 Original Article Developing a list of important drug- drug interactions in the clinical practice in the internal department – Kien An Hospital, Hai Phong City Nguyen Thi Hanh1, Vu Thi Phuong Thao2, Ha Quang Tuan3, Nguyen Xuan Bach4, Nguyen Thanh Hai1,* 1 Hanoi University of Pharmacy, 13-15 Le Thanh Tong, Hoan Kiem, Hanoi, Vietnam 2 Haiphong University of Medicine and Pharmacy, 72A Nguyen Binh Khiem, Ngo Quyen, Hai Phong, Vietnam 3 Pharmacy Department of Kien An Hospital, 15 Tran Tat Van, Kien An, Hai Phong, Vietnam 4 VNU School of Medicine and Pharmacy, 144 Xuan Thuy, Cau Giay, Hanoi, Vietnam Received 04 October 2019 Revised 25 November 2019; Accepted 04 Deceber 2019 Abstract: This study was aimed to develop a list of important drug- drug interactions (DDIs) at the Internal department – Kien An Hospital. Subjects and methods: This study was 3 phases: (1) The construction of the initiative list was based on consenous of the documentations from the list of drugs in Kien An hospital: Micromedex , the patient leaflets and Drug Interaction Fact 2014. (2) The research group reviewed all the in-patient medical records in the General internal department and Cardiology department and sorted the high-frequency DDIs with prevalance higher than 1%. (3) After the DDIs of the first list and the second list were assessed by a group of doctors and pharmacists who the proposed a list of important DDIs at the internal deparment – Kien An Hospital. Results: From the documentations, the research group constructed 27 DDIs of the list. Conclusion: This DDIs list can be disseminated in clinical departments and integrated into the prescribing software of Kien An hospital. Keywords: Kien An hospital, DDIs, .