Genomic selection (GS) is a form of marker-assisted selection in which genetic markers covering the whole genome are used so that all quantitative trait loci (QTL) are in linkage disequilibrium with at least one marker. With advances in molecular biology and marker technology, a new era of molecular breeding has emerged that has greatly accelerated the pace of plant breeding. Wholegenome prediction models estimate all marker effects in all loci and capture small QTL effects. Here, we review difference between MAS and Genomic selection (GS) along with GS models with respect to both the prediction accuracy and genetic gain from selection.