Aims of the study are to detect biofilm producing Staphylococcus epidermidis isolated from various clinical specimens. Total 73 Staphylococcus epidermidis isolates were collected from clinical samples like blood, post-operative wound swabs, IV catheter tips, catheterized urine, and exudates received from various clinical departments. The study was carried out over a period of one year. | Biofilm detection and clinical significance of Staphylococcus epidermidis Isolates in a tertiary care hospital Karimnagar India