Cholangiocarcinoma (CCA) may arise in the intra- or extrahepatic biliary tract and is associated with a poor prognosis. Despite recent advances, to date there is still no established targeted therapeutic approach available. Non-surgical therapeutic agents are urgently needed, as most patients are non-eligible to surgical resection. | Programmed cell death ligand 1 PD-L1 CD274 in cholangiocarcinoma correlation with clinicopathological data and comparison of antibodies