This study was done at SIMS and PG Research Centre, Hyderabad. The aim of the study is to find out the incidence of Hepatitis B surface antigen in antenatal women of SIMS during the period of 23 months from January 1st 2015 to November 2016. A total of 7096 antenatal women were tested for HBs Ag. out of these 57 pregnant women were found to be positive for Hbs Ag (). In pregnancy, Hepatitis B infection with complications to the pregnant women and has the risk of transmission to the baby; which makes it mandatory to screen all antenatal women and their pregnancy should be managed properly and for the newborn immunoprophylaxis is to be given. | Incidence of hepatitis B surface antigen in antenatal cases in a tertiary care hospital in Hyderabad telangana state India