The present study explores the bioconversion by Geotrichum candidum of five amino acids to their corresponding α-keto acids used in the treatment of chronic kidney disorder. The amino acid oxidase activity biotransforming amino acids to α-keto acids was detected in biomass as well as extracellular culture fluids of G. candidum. Bioconversion was determined by measuring α-keto acid production along with residual amino acid. There was a 2-fold increase in the amount of α-keto acids produced over a period of 24 hours by permeabilization of biomass when compared to immobilized biomass. | Bioconversion of amino acids to α-Keto acid by Geotrichum candidum used for the treatment of chronic kidney disorders
