Tuyển tập các báo cáo nghiên cứu khoa học quốc tế về bệnh thú y đề tài: Efficiency of Matricaria chamomilla CH12 and number of doses of rabies vaccine on the humoral immune response in cattle | J. Vet. Sci. 2008 9 4 433-435 JOURNAL OF Case Report Veterinary Science Efficiency of Matricaria chamomilla CH12 and number of doses of rabies vaccine on the humoral immune response in cattle 1. 2 1 2 3 Luis Souza Lima de Souza Reis . Neuza Maria Frazatti-Gallina . Rosana de Lima Paoli. Rogerio Giuffrida . Avelino Albas4. Eunice Oba5. Paulo Eduardo Pardo1 1Universidade do Oeste Paulista-UNOESTE Pós-graduẹão em Ciência Animal Presidents Prudente-SP CEP 19067-175 Brazil 2Seẹão de Raiva do Instituto Butantan São Paulo-SP CEP 05503-900 Brazil 3Universidade do Oeste Paulista UNOESTE Laboratório de Medicina Veterinária Preventiva Presidente Prudente-SP CEP 19067-175 Brazil 4Agência Paulista de Tecnologia dos Agronegócios Presdente Prudente São Paulo CEP 19100-000 Brazil 5Universidade EstadualPaulista Julio deMesquitaFilho-UNESP FMVZ Departamento de Reproduẹão Animal eRadiologia Botucatu São Paulo CEP 18618-000 Brazil This study evaluated the effect of Matricaria chamomilla and vaccination frequency on cattle immunization against rabies. Four groups n 15 group were treated with or without Matricaria chamomilla CH12 and vaccinated with one or two doses of rabies vaccine 30 day interval . No effect of chamomile was found on cattle immunization against rabies however. antibody titers were protective in cattle vaccinated twice. while of cattle vaccinated only once had titers under Ul ml after 60 days. In conclusion. the use of chamomile did not alter the humoral immune response in cattle. and two vaccine doses are suggested for achieving protective antibody titers. Keywords cattle immune response Matricaria chamomilla rabies vaccine Rabies is one of the most serious zoonoses in the world because it consists of fatal encephalitis that may be found in mammals and occurs within a wide geographical range 1 4 . It is caused by a virus belonging to the genus Lyssavirus of the family Rhabdoviridae 7 8 and is transmitted mainly by the hematophagous bat Desmodus rotundus in .
