Tuyển tập các báo cáo nghiên cứu khoa học ngành y học tạp chí Medical Sciences dành cho các bạn sinh viên ngành y tham khảo đề tài: A Practical Approach to Managing Patients with HCV Infection. | Int. J. Med. Sci. 2006 3 63 Review International Journal of Medical Sciences ISSN 1449-1907 2006 3 2 63-68 2006 Ivyspring International Publisher. All rights reserved A Practical Approach to Managing Patients with HCV Infection Richard H. Huang and Ke-Qin Hu Division of Gastroenterology and Hepatology University of California Irvine Medical Center CA 92868 USA Corresponding address Ke-Qin Hu MD Director of Hepatology Services and Associate Professor of Clinical Medicine Division of Gastroenterology Univ. of California Irvine Medical Center 101 The City Drive Building 53 Suite 113 Orange CA 92868 USA. Phone 714-456-6745. Email kqhu@ Received Accepted Published Hepatitis C virus HCV infection is a major worldwide public health concern. It is a common cause of chronic liver disease and hepatocellular carcinoma. hCv antibody and HCV RNA testing are available diagnostic studies that offer high degree of accuracy. Current standard therapy includes a combination of pegylated interferon and ribavirin. Response rate is approximately 40 for genotype 1 and 80 for genotypes 2 and 3 respectively. Successful treatment can stop the progression of chronic liver disease reduce the need for liver transplantation and possibly decrease the risk for Hepatocellular carcinoma HCC . Evaluating for potential treatment candidacy is an important initial step in the management of chronic HCV infection as not all individuals may need or qualify for the treatment. Understanding the natural history the different diagnostic modalities the current therapeutic options and the treatment response and adverse effect profiles can help the practitioners better manage chronic HCV infection. Key words Chronic Hepatitis C treatment interferon PEG-interferon ribavirin 1. Introduction Hepatitis C virus HCV infection formerly known as non-A non-B hepatitis was first identified in 1988. The WHO estimates that over 170 million people globally are .
