Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: | Yu et al. World Journal of Surgical Oncology 2011 9 45 http content 9 1 45 5 T WORLD JOURNAL OF SURGICAL ONCOLOGY CASE REPORT Open Access Thick calcification from a GIST of the stomach penetrating into pericolic soft tissue - report of a case Cheng-Chan Yu1 Cheng-Chung Wu1 Jen-I Hwang2 John Wang3 and Chi-Sen Chang4 Abstract Thick calcification is a rare presentation of gastrointestinal stromal tumor GIST . Penetration into gastric mucosa and pericolic soft tissue has never been reported. We report a case of gastric GIST with cystic degeneration and thick calcification in an 81-year old female who presented with hematemesis and severe abdominal pain. Thick calcification of this tumor penetrating into pericolic soft tissue was noted and successfully treated by distal gastrectomy and partial colectomy. For gastrointestinal tumors with thick calcification even with benign behavior surgical intervention should be considered for both oncological considerations and prevention of catastrophes like perforation or penetration into surrounding soft tissue. Introduction Calcification within primary gastrointestinal stromal tumor GIST has been reported 1-3 but thick calcification within GIST is rare 1 . Thick calcification of a GIST penetrating into surrounding soft tissue has never been reported. Herein we report the first case of thick calcification from a gastric GIST with cystic degeneration penetrating into pericolic soft tissue. Case presentation An 81-year-old female with hypertension and gout was admitted to Taichung Veterans General Hospital due to abdominal pain and hematemesis. She began to suffer from intermittent epigastralgia more than 10 years ago and a 4 cm gastric tumor was found. The abdominal pain got worse 2 years before admission and she went to a local hospital where abdominal CT scan revealed a gastric tumor about 6 cm in length with well-circumscribed calcification figure 1 . Surgical intervention was suggested but she declined. About 10 .