Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Highly malignant soft tissue sarcoma of the extremity with a delayed diagnosis | Park et al. World Journal of Surgical Oncology 2010 8 84 http content 8 1 84 WORLD JOURNAL OF SURGICAL ONCOLOGY RESEARCH Open Access Highly malignant soft tissue sarcoma of the extremity with a delayed diagnosis 1 2 3 1 1 Jong Hoon Park Chang Ho Kang Chul Hwan Kim In Jung Chae Ji Hun Park Abstract Purpose To evaluate the characteristics of highly malignant soft tissue sarcoma of the extremity with a delayed diagnosis. Materials and methods The clinical and radiological characteristics of 18 cases of highly malignant soft tissue sarcomas of the extremity with a delayed diagnosis were determined. Results Ten men and eight women of mean age years range 15-79 years were included in this study. Seven cases of synovial sarcoma three cases each of alveolar soft part sarcoma and malignant fibrous histiocytoma two cases each of highly malignant leiomyosarcoma and myxofibrosarcoma and one case of clear cell sarcoma were enrolled. Times from tumor detection to diagnosis ranged from 1 to 3 years in most cases three of the seven synovial sarcoma cases took more than 10 years to diagnose. Of the seven cases of synovial sarcoma five cases of small superficial located masses were simply excised without a pre-surgical biopsy. Three cases of alveolar soft part sarcoma showed characteristic T1- and T2-weighted high signal intensities with signal voids in MR images. In addition one synovial sarcoma patient and one alveolar soft part sarcoma patient showed evidence of calcification on plain radiographs. However no general characteristic clinical findings were found to be common to the 18 cases. Conclusions Contrary to general expectations some soft tissue tumors that grow slowly are painless and those that occur in superficial limbs may be highly malignant. Thus even when a slow growing painless superficial mass is encountered in a limb physicians should keep the possibility of highly malignant soft tissue sarcoma in mind. Introduction Soft tissue sarcomas that .
