Báo cáo y học: "Capturing real-life patient care in psoriatic arthritis and its risks: the challenge of analysing registry data"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học General Psychiatry cung cấp cho các bạn kiến thức về ngành y đề tài:Capturing real-life patient care in psoriatic arthritis and its risks: the challenge of analysing registry data. | Available online http content 11 3 112 Editorial Capturing real-life patient care in psoriatic arthritis and its risks the challenge of analysing registry data Daniel Aletaha Division of Rheumatology Medical University of Vienna Vienna Austria Corresponding author Daniel Aletaha Published 3 June 2009 Arthritis Research Therapy 2009 11 112 doi ar2694 This article is online at http content 11 3 112 2009 BioMed Central Ltd See related research by Saad et al. http content 11 2 R52 Abstract Studies based on registries continue to inform us of many relevant issues in the treatment of arthritic conditions and constitute more than just a supplement of clinical trial data. We can learn about long-term aspects of therapies beyond the scope of most clinical trials and about larger-scale toxicity. The downsides need to be considered in the interpretation of the results and include mainly the biases that are inherent when routine clinical practice is just observed and not steered by a protocol. However using steered protocols in practice not only would facilitate post hoc analyses of clinical effectiveness but as we have learned from research in rheumatoid arthritis can also improve outcomes of our patients. In a recent issue of Arthritis Research Therapy Saad and colleagues 1 present a study on the persistence with antitumour necrosis factor anti-TNF therapy in psoriatic arthritis PsA . And as is the case for most publications that stem from registries there will be those excited about learning important real-life aspects of our therapies and there will be those critical about it citing all of the biases of observational studies that can be reviewed in epidemiological textbooks. What unites these different viewpoints is that we have become increasingly aware in the past decades that there are certain things and medical facts that we will never learn from clinical trials

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