Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học 'Respiratory Research cung cấp cho các bạn kiến thức về ngành y đề tài: " Bronchiolar chemokine expression is different after single versus repeated cigarette smoke exposure. | Respiratory Research BioMed Central Research Open Access Bronchiolar chemokine expression is different after single versus repeated cigarette smoke exposure Tomoko Betsuyaku 1 Ichiro Hamamura2 Junko Hata2 Hiroshi Takahashi2 Hiroaki Mitsuhashi2 Tracy L Adair-Kirk3 Robert M Senior3 and Masaharu Nishimura1 Address 1First Department of Medicine Hokkaido University School of Medicine Kita-15 Nishi-7 Kita-ku Sapporo 060-8683 Japan 2Teijin Institute for Bio-medical Research Teijin Pharma Ltd. 4-3-2 Asahigaoka Hino Tokyo 191-8512 Japan and 3Division of Pulmonary and Critical Care Medicine Department of Medicine Washington University School of Medicine and Barnes-Jewish Hospital 660 So. Euclid Avenue St. Louis MO 63110 USA Email Tomoko Betsuyaku - bytomoko@ Ichiro Hamamura - Junko Hata - Hiroshi Takahashi - Hiroaki Mitsuhashi - Tracy L Adair-Kirk - tkirk@ Robert M Senior - seniorr@ Masaharu Nishimura - ma-nishi@ Corresponding author Published 21 January 2008 Received 3 September 2007 Respiratory Research 2008 9 7 doi l465-992l-9-7 Accepted 21 January 2008 This article is available from http content 9 l 7 2008 Betsuyaku et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background Bronchioles are critical zones in cigarette smoke CS -induced lung inflammation. However there have been few studies on the in vivo dynamics of cytokine gene expression in bronchiolar epithelial cells in response to CS. Methods We subjected C57BL 6J mice to CS whole body exposure 90 min day for various periods and used laser capture .
