Báo cáo y học: " Immune sensitization of equine bronchus: glutathione, IL-1β expression and tissue responsiveness"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Retrovirology cung cấp cho các bạn kiến thức về ngành y đề tài: " Immune sensitization of equine bronchus: glutathione, IL-1β expression and tissue responsiveness. | Respiratory Research BioMed Central Research Open Access Immune sensitization of equine bronchus glutathione IL-1 p expression and tissue responsiveness MG Matera1 L Calzetta2 A Peli3 A Scagliarini4 C Matera5 and M Cazzola 2 Address Department of Experimental Medicine Unit of Pharmacology 2nd University of Naples Naples Italy 2Department of Respiratory Medicine Unit of Pneumology and Allergology A. Cardarelli Hospital Naples Italy 3Department of Veterinary Clinical Science Faculty of Veterinary Medicine University of Bologna Bologna Italy 4Department of Veterinary Public Health and Animal Pathology Faculty of Veterinary Medicine University of Bologna Bologna Italy and 5Department of Pharmaceutical Sciences Santissima Annunziata Hospital Chieti Italy Email MG Matera - L Calzetta - luigicalz@ A Peli - apeli@ AScagliarini - ascaglierini@ C Matera - mascite@ M Cazzola - mcazzola@ Corresponding author Published 15 September 2005 Received 07 February 2005 Respiratory Research 2005 6 104 doi 1465-9921-6-104 Accepted I5 September 2005 This article is available from http content 6 1 104 2005 Matera et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background Increasing clinical epidemiological and experimental evidence indicates that excess of production of reactive oxygen free radicals ROS induced by an oxidative stress is involved in the pathogenesis of a number of human airway disorders as well as equine recurrent airway obstruction. Free-radicals modulate the activation of transcription factors such as nuclear factor- NF -kB and activator protein AP -1 in several different cells. This activation .

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