Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Critical Care giúp cho các bạn có thêm kiến thức về ngành y học đề tài: Central venous oxygen saturation and emergency intubation another piece in the puzzle? | Available online http content 13 4 172 Commentary Central venous oxygen saturation and emergency intubation -another piece in the puzzle Wolfgang Stahl 1 Peter Radermacher2 Michael Georgieff1 and Hendrik Bracht1 1Universitătsklinik fur Anăsthesiologie Universităt Ulm SteinhovelstraBe 89073 Ulm Germany 2Sektion APV Universitătsklinik fur Anăsthesiologie Universităt Ulm SteinhovelstraBe 89073 Ulm Germany Corresponding author Hendrik Bracht Published 3 August 2009 This article is online at http content 13 4 172 2009 BioMed Central Ltd Critical Care 2009 13 172 doi cc7915 See related research by Hernandez et al. http content 13 3 R63 Abstract A recent multicentre observational study examined the effect of emergency intubation on central venous oxygen saturation Scvo2 in critically ill patients. The main finding was that Scvo2 significantly increases 15 minutes after emergency intubation and institution of mechanical ventilation with 100 oxygen especially in those patients with pre-intubation Scvo2 values 70 regardless of whether these patients suffered from severe sepsis. However in only one-quarter of this subgroup was the Scvo2 normalized to 70 solely by this intervention. In contrast in patients with pre-intubation Scvo2 70 the Scvo2 failed to increase after intubation. A rise in Scvo2 can be expected when whole body oxygen extraction remains unchanged after intubation and ventilation with pure oxygen. The value of central venous oxygen saturation Scvo2 remains a matter of debate and Hernandez and coworkers 1 have contributed another piece of the puzzle with their study on the effects of emergency intubation on Scvo2 in critically ill patients. Since the work presented a few years ago by Rivers and colleagues 2 early goal-directed therapy EGDT which they found to be associated with significantly improved outcome in sepsis has been considered as a fundamental strategy in the initial .
