Báo cáo y học: "International recommendations for glucose control in adult non diabetic critically ill patients"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học quốc tế cung cấp cho các bạn kiến thức về ngành y đề tài: International recommendations for glucose control in adult non diabetic critically ill patients. | Ichai et al. Critical Care 2010 14 R166 http content 14 5 R166 c CRITICAL CARE RESEARCH Open Access International recommendations for glucose control in adult non diabetic critically ill patients 1 2 3 Carole Ichai Jean-Charles Preiser for the Société Frangaise d Anesthésie-Réanimation SFAR Société de Réanimation de langue Frangaise SRLF and the Experts group4 Abstract Introduction The purpose of this research is to provide recommendations for the management of glycemic control in critically ill patients. Methods Twenty-one experts issued recommendations related to one of the five pre-defined categories glucose target hypoglycemia carbohydrate intake monitoring of glycemia algorithms and protocols that were scored on a scale to obtain a strong or weak agreement. The GRADE Grade of Recommendation Assessment Development and Evaluation system was used with a strong recommendation indicating a clear advantage for an intervention and a weak recommendation indicating that the balance between desirable and undesirable effects of an intervention is not clearly defined. Results A glucose target of less than 10 mmol L is strongly suggested using intravenous insulin following a standard protocol when spontaneous food intake is not possible. Definition of the severe hypoglycemia threshold of mmol L is recommended regardless of the clinical signs. A general unique amount of glucose enteral parenteral to administer for any patient cannot be suggested. Glucose measurements should be performed on arterial rather than venous or capillary samples using central lab or blood gas analysers rather than point-of-care glucose readers. Conclusions Thirty recommendations were obtained with a strong 21 and a weak 9 agreement. Among them only 15 were graded with a high level of quality of evidence underlying the necessity to continue clinical studies in order to improve the risk-to-benefit ratio of glucose control. Introduction Critically ill patients in intensive care units .

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