Trong đặc hữu vùng sốt rét, sốt sốt rét là nguyên nhân phổ biến nhất của các cơn động kinh feverrelated, mặc dù một số cho rằng cơn động kinh xảy ra trong thiết lập này là những triệu chứng của chính sự tham gia của hệ thống thần kinh trung ương chứ không phải là động kinh do sốt. | EPILEPSY GLOBAL ISSUES FOR THE PRACTICING NEUROLOGIST KEYPOINTS In malaria-endemic regions malarial fevers are the most common cause of fever-related seizures although some argue that seizures occurring in this setting are symptoms of primary central nervous system involvement rather than a febrile seizure. and Latin America indicate that people with epilepsy have less access to education employment and marriage than their unaffected counterparts. Some countries even list epilepsy as lawful grounds for divorce. Febrile Seizures Febrile seizures FSs are seizures that occur in association with fever in children between 6 months and 5 years of age. Most often FSs occur during the second year of life. To diagnose FS the fever should not be due to any intracranial infection including meningitis or encephalitis. In malariaendemic regions malarial fevers are the most common cause of fever-related seizures although some argue that seizures occurring in this setting are symptoms of primary central nervous system CNS involvement rather than a FS. FSs have been classified as simple or complex. Complex FSs include seizures with focal onset a single FS lasting for more than 15 minutes or recurrent FS within 24 hours. Important risk factors predicting recurrence of FS are a young age of onset b evidence of developmental delay c family history of FS among first-degree relatives and d low grade fever for a short duration before the febrile seizure occurred. Data from developed countries indicate that FSs occur in about 3 to 4 of all children. Most FSs are benign events as only about 5 of all children with FS develop epilepsy. The risk of epilepsy is estimated to be following a simple FS compared to 8 to 15 after a complex FS. Risk factors associated with the development of epilepsy after FS include a evidence of developmental delay and b family history of epilepsy. Fever-associated seizures may be more common in developing countries especially in regions with endemic P. .
