Báo cáo y học: " Acceptability of Carraguard, a candidate microbicide and methyl cellulose placebo vaginal gels among HIV-positive women and men in Durban, South Africa"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Wertheim cung cấp cho các bạn kiến thức về ngành y đề tài: Acceptability of Carraguard, a candidate microbicide and methyl cellulose placebo vaginal gels among HIV-positive women and men in Durban, South Africa. | AIDS Research and Therapy BioMed Central Research Open Access Acceptability of Carraguard a candidate microbicide and methyl cellulose placebo vaginal gels among HIV-positive women and men in Durban South Africa Gita Ramjee 1 Neetha S Morar1 Sarah Braunstein2 Barbara Friedland2 Heidi Jones2 and Janneke van de Wijgert2 3 Address 1Medical Research Council P O Box 70380 Overport 4067 Kwazulu-Natal South Africa 2Population Council One Dag Hammarskjold Plaza New York New York 10017 USA and 3Academic Medical Center Center for Poverty-related Communicable Diseases University of Amsterdam Meibergdreef 9 PO Box 22700 1100 DE Amsterdam the Netherlands Email Gita Ramjee - Neetha S Morar - Sarah Braunstein - SBRAUNSTEIN@ Barbara Friedland - BFRIEDLAND@ Heidi Jones - hej2103@ Janneke van de Wijgert - Corresponding author Published 27 September 2007 Received 24 July 2007 AIDS Research and Therapy 2007 4 20 doi 1742-6405-4-20 Accepted 27 September 2007 This article is available from http content 4 1 20 2007 Ramjee et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background and Methods When on the market microbicides are likely to be used by individuals who do not know their HIV status. Hence assessment of safety and acceptability among HIV positive men and women is important. Acceptability of Carraguard the Population Council s lead microbicide candidate was assessed in a Phase I safety study among healthy HIV-positive sexually abstinent women and men and sexually active women 20 per group in Durban South Africa. Participants were randomized to use Carraguard gel placebo gel or no .

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