Báo cáo y học: "Preoperative ejection fraction as a predictor of survival after coronary artery bypass grafting: comparison with a matched general population"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Wertheim cung cấp cho các bạn kiến thức về ngành y đề tài: Preoperative ejection fraction as a predictor of survival after coronary artery bypass grafting: comparison with a matched general population. | Soliman Hamad et al. Journal of Cardiothoracic Surgery 2010 5 29 http content 5 1 29 Jdfrs JOURNAL OF CARDIOTHORACIC SURGERY RESEARCH ARTICLE Open Access Preoperative ejection fraction as a predictor of survival after coronary artery bypass grafting comparison with a matched general population Mohamed A Soliman Hamad 1 Albert HM van Straten1 Jacques PAM Schonberger1 Joost F ter Woorst1 Andre M de Wolf2 Elisabeth J Martens3 4 and André AJ van Zundert5 6 Abstract Background Preoperative left ventricular dysfunction is an established risk factor for early and late mortality after revascularization. This retrospective analysis demonstrates the effects of preoperative ejection fraction on the shortterm and long-term survival of patients after coronary artery bypass grafting. Methods Early and late mortality were determined retrospectively in 10 626 consecutive patients who underwent isolated coronary bypass between January 1998 and December 2007. The subjects were divided into 3 groups according to their preoperative ejection fraction. Expected survival was estimated by comparison with a general Dutch population group described in the database of the Dutch Central Bureau for Statistics. For each of our groups with a known preoperative ejection fraction a general Dutch population group was matched for age sex and year of operation. Results and Discussion One hundred twenty-two patients were lost to follow-up. In 219 patients the preoperative ejection fraction could not be retrieved. In the remaining patients n 10 285 the results of multivariate logistic regression and Cox regression analysis identified the ejection fraction as a predictor of early and late mortality. When we compared long-term survival and expected survival we found a relatively poorer outcome in all subjects with an ejection fraction of 50 . In subjects with a preoperative ejection fraction of 50 long-term survival exceeded expected survival. Conclusions The severity of .

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