Báo cáo y học: "Initial experience with off-pump left ventricular assist device implantation in single center: retrospective analysis"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Wertheim cung cấp cho các bạn kiến thức về ngành y đề tài: Initial experience with off-pump left ventricular assist device implantation in single center: retrospective analysis. | Awad et al. Journal of Cardiothoracic Surgery 2010 5 123 http content 5 1 123 JCTS JOURNAL OF CARDIOTHORACIC SURGERY RESEARCH ARTICLE Open Access Initial experience with off-pump left ventricular assist device implantation in single center retrospective analysis 1 1 2 1 3 r z- - 4 Hamdy Awad Mohamed Abd El Dayem Jarrett Heard Galina Dimitrova Lianbo Yu Benjamin C Sun Abstract Background We hypothesize that implantation of left ventricular assist device through off-pump technique is feasible and has a comparable result to implantation on cardiopulmonary bypass and could improve one-year survival. Methods This retrospective observational single-center study was conducted on 29 consecutive patients at our institution who underwent off-pump left ventricular assist device implantation by a single surgeon. Results Twenty-seven procedures were performed successfully using the off-pump technique. The survival rate was 92 at 30 days 76 at 90 days and 67 at one year. We compared the one-year survival of different implantation periods and divided our study into three time intervals 2004-2005 2006 and 2007 . There was a trend in reduction in number of deaths over one year that demonstrated a decrease in death rate from 50 to 17 as well as improvement in our experience over time. However this trend is not statistically significant p due to limited sample size. Conclusions Based upon our findings off-pump left ventricular assist device implantation is a feasible surgical technique and combining this technique with improved device technology in the future may provide even greater improvement in patient outcomes. Background Left ventricular assist devices were approved as a bridge to transplantation therapy BTT in 1998 1 . In 2001 they became a destination therapy in the United States 2 . Perioperative complications result from a combination of three factors 1 intrinsic heart failure with secondary organ damage 2 long-term effect of the implanted

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