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Báo cáo y học: "Endotoxin receptor CD14 in PiZ α-1-antitrypsin deficiency individuals"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học 'Respiratory Research cung cấp cho các bạn kiến thức về ngành y đề tài: " Endotoxin receptor CD14 in PiZ α-1-antitrypsin deficiency individuals. | Respiratory Research BioMed Central Research Open Access Endotoxin receptor CDI4 in PiZ a-l-antitrypsin deficiency individuals Caroline S Sandstrom1 Natalia Novoradovskaya2 Corrado M Cilio3 Eeva Piitulainen4 Tomas Sveger5 and Sabina Janciauskiene 1 Address Department of Clinical Sciences Chronic and Degenerative Disease Research Unit University Hospital Malmoe Lund University S-20502 Malmo Sweden 2Stratagene Agilent Technologies Company 11011 North Torrey Pines Road La Jolla CA 92037 USA 3Department of Clinical Sciences Cellular Autoimmunity Unit University Hospital Malmoe Lund University S-20502 Malmo Sweden 4Department of Respiratory Medicine and Allergology University Hospital Malmoe Lund University S-20502 Malmoe Sweden and 5Department of Clinical Sciences Preventive Paediatrics University Hospital Malmoe Lund University S-20502 Malmoe Sweden Email Caroline S Sandstrom - Caroline.Sandstrom@med.lu.se Natalia Novoradovskaya - Natalia.Novoradovskaya@stratagene.com Corrado M Cilio - Corrado.Cilio@med.lu.se Eeva Piitulainen - Eeva.Piitulainen@med.lu.se Tomas Sveger - Tomas.Sveger@med.lu.se Sabina Janciauskiene - Sabina.Janciauskiene@med.lu.se Corresponding author Published 21 April 2008 Received 13 February 2008 Respiratory Research 2008 9 34 doi 10.1186 1465-9921 -9-34 Accepted 21 April 2008 This article is available from http respiratory-research.eom content 9 1 34 2008 Sandstrom et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http creativecommons.org licenses by 2.0 which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background CD14 a receptor for lipopolysaccharides LPS is found in both a membrane-bound form mCD14 and a soluble form sCD14 . It is suggested that sCD14 is mainly released from blood monocytes by serine protease-mediated shedding. Because a1-antitrypsin AAT an inhibitor of serine .