Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Critical Care giúp cho các bạn có thêm kiến thức về ngành y học đề tài: Increased blood lacate levels: an important warning signal in surgical practice. | Critical Care April 2004 Vol 8 No 2 Bakker and Pinto de Lima Commentary Increased blood lacate levels an important warning signal in surgical practice Jan Bakker1 and Alex Pinto de Lima2 1 Head Department of Intensive Care Erasmus Medical Center Rotterdam The Netherlands 2Research Physician Department of Intensive Care Erasmus Medical Center Rotterdam The Netherlands Correspondence Jan Bakker Published online 3 March 2004 Critical Care 2004 8 96-98 DOI cc2841 This article is online at http content 8 2 96 2004 BioMed Central Ltd Print ISSN 1364-8535 Online ISSN 1466-609X Abstract Both in emergency and elective surgical patients increased blood lactate levels warn the physician that the patient is at risk of increased morbidity and decreased changes of survival. Prompt therapeutic measures to restore the balance between oxygen demand and supply are warranted in these patients. Keywords lactate lactic acid morbidity mortality trauma surgery When first described by Gaglio in 1886 measurement of lactate levels required the collection of 100-200 ml blood and took several days to complete. The labour-intensive nature of early lactate measurement techniques limited their clinical use because results were not available until long after therapeutic decisions had to be made. In 1964 Broder and Weil 1 were the first to use a photospectrometric method to measure lactate levels in whole blood decreasing turnaround times greatly. Current handheld devices and mobile blood gas analyzers have decreased turnaround time to less than 2 min using a minimal amount of blood 2 . With this technology it is possible to diagnose treat and monitor critically ill patients rapidly and easily. A relationship between increased blood lactate levels and the presence of oxygen debt tissue hypoxia in patients with circulatory shock was suggested as early as 1927 3 . In patients with clinical shock associated with tachycardia hypotension cold and clammy skin
