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Báo cáo y học: "Progressive obtundation in a young woman with bilateral corpus striatum infarction: a case report"

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Progressive obtundation in a young woman with bilateral corpus striatum infarction: a case report. | Amin et al. Journal of Medical Case Reports 2011 5 324 http www.jmedicalcasereports.eom content 5 1 324 JOURNAL OF MEDICAL CASE REPORTS CASE REPORT Open Access Progressive obtundation in a young woman with bilateral corpus striatum infarction a case report Osama SM Amin1 Sa ad Seud Shwani1 Hero M Zangana1 and Nawa A Ameen2 Abstract Background Bilateral ischemic infarction involving the corpus striatum is a rare event which usually results from global cerebral hypoxia intoxications and drug abuse. Case presentation We report a 28 year old Caucasian woman who presented with progressive obtundation and later development of severe expressive dysphasia and Parkinsonism after sustaining ischemic stroke of both corpora striata. Hemorrhagic transformation developed on day four of admission. Conclusion This is a rare case of bilateral basal ganglia infarction with hemorrhagic transformation in a young patient. Our patient s work up did not reveal any cause behind this stroke however advanced investigations such as genetic testing and conventional angiography were not done. The damage resulted in motor dysphasia and Parkinsonism. Neither dystonia nor other involuntary movements developed and cognitive function was not assessed because of the language disorder. Background The human basal ganglia which have a complex anatomy and physiology are supplied by several blood vessels on either side. Bilateral ischemic infarction involving the corpus striatum is a rare event which usually results from global cerebral hypoxia intoxications and drug abuse. Case report A 28 year old Caucasian woman was brought to our emergency department with a five hour history of progressive impairment in consciousness and slurred speech. Her past history was unremarkable and she neither smoked nor drank alcohol. Her older brother said that she took no medications and she did not use illicit drugs as far as he knew. No history of head trauma was obtained. At the time of admission her blood pressure was