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Báo cáo y học: "Colonic adenocarcinoma revealing Crohn's disease: a case report Case report"

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Colonic adenocarcinoma revealing Crohn's disease: a case report Case report. | Ankouz et al. Journal of Medical Case Reports 2010 4 167 http www.jmedicalcasereports.eom content 4 1 167 jA JOURNALOF.MEDICAL CASE REPORTS CASE REPORT Open Access Co lonic adenocarcinoma revealing Crohn s disease a case report Amal Ankouz Karim Ibn Majdoub AbdelmalekOusadden Khalid Mazaz and Khalid Ait Taleb Abstract Introduction There is growing evidence from epidemiological studies and clinicopathological data obtained from case reports that Crohn s disease is associated with an increased risk of carcinoma of the large bowel. Case presentation A 70-year-old Arabic African man with undiagnosed Crohn s disease presented with acute abdominal obstruction due to an occlusive carcinoma of the sigmoid. At laparotomy the colonic tumor was excised with continuity restored by end-to-end anastomosis. Conclusion The risk of colonic carcinoma in Crohn s disease is increasing. Several case reports actually support the possibility that a genuine association between these two conditions exists. Introduction Colorectal cancer occurring in ulcerative colitis was described in 1925 by Crohn 1 but not until 23 years later did Warren and Sommers report the first case of adenocarcinoma complicating regional enteritis 2 . For the next 30 years an increasing frequency of reports of single 3 4 and even multiple cases 4 5 failed to dispel the scepticism surrounding this association. Case report A 70-year-old Arabic African man presented to the emergency department of the University Hospital Hassan II of Fez with a five-day intestinal obstruction with associated abdominal distension and vomiting. He denied intestinal bleeding or diarrhea. He gave a history of referred intermittent episodes of constipation for a period of 6 months. When examined he was found to have general abdominal tenderness. His white blood cell count was 8000 elt ml his haemoglobin was 11 gr dl and his platelet count was 350 k ml. His abdominal X-rays showed air-fluid levels. Abdominal scanner examination revealed a .