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báo cáo khoa học: "An overview of tissue engineering approaches for management of spinal cord injuries"

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: An overview of tissue engineering approaches for management of spinal cord injuries | Journal of NeuroEngineering and Rehabilitation BioMed Central Open Access Review An overview of tissue engineering approaches for management of spinal cord injuries Ali Samadikuchaksaraei Address Consultant in Tissue Engineering and Regenerative Medicine Consultant in General Medicine Assistant Professor Department of Biotechnology Faculty of Allied Medicine and Cellular and Molecular Research Center Iran University of Medical Sciences Iran Email Ali Samadikuchaksaraei - samadikuchaksaraei@yahoo.com Corresponding author Published 14 May 2007 Received 8 May 2006 Journal of NeuroEngineering and Rehabilitation 2007 4 15 doi l0.ll86 l743-0003-4-l5 Accepted I4 May 2007 This article is available from http www.jneuroengrehab.cOm content 4 l l5 2007 Samadikuchaksaraei licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http creativecommons.org licenses by 2.0 which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract_ Severe spinal cord injury SCI leads to devastating neurological deficits and disabilities which necessitates spending a great deal of health budget for psychological and healthcare problems of these patients and their relatives. This justifies the cost of research into the new modalities for treatment of spinal cord injuries even in developing countries. Apart from surgical management and nerve grafting several other approaches have been adopted for management of this condition including pharmacologic and gene therapy cell therapy and use of different cell-free or cell-seeded bioscaffolds. In current paper the recent developments for therapeutic delivery of stem and nonstem cells to the site of injury and application of cell-free and cell-seeded natural and synthetic scaffolds have been reviewed. Introduction .