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Báo cáo y học: "A 47-year-old man with neuro-Sweet syndrome in association with Crohn’s disease: a case report"

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài:A 47-year-old man with neuro-Sweet syndrome in association with Crohn’s disease: a case report | JOURNAL OF MEDICAL Sr CASE REPORTS Open Access Case report A 47-year-old man with neuro-Sweet syndrome in association with Crohn s disease a case report Nadine Hiari and Colin Borland Address Hinchingbrooke Hospital Huntingdon PE29 6NT UK Email NH - nmah2@cantab.net CB - colin.borland@hinchingbrooke.nhs.uk Corresponding author Received 29 July 2008 Accepted 11 June 2009 Published 10 September 2009 Journal ofMedical Case Reports 2009 3 8997 doi 10.4076 1752-1947-3-8997 This article is available from http jmedicalcasereports.com jmedicalcasereports article view 8997 2009 Hiari and Borland licensee Cases Network Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http creativecommons.org licenses by 3.0 which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Introduction Sweet s syndrome is a multi-system inflammatory disorder characterised by painful skin lesions and aseptic neutrophilic infiltration of various organs. We describe a case of Sweet s syndrome with aseptic meningitis in association with Crohn s disease neuro-Sweet syndrome . This association has never been previously reported. Case presentation A 47-year-old Caucasian male with known Crohn s disease presented with headache fever and skin lesions resembling erythema nodosum. The cerebrospinal fluid revealed leukocyte pleocytosis and dominant neutrophils but cultures were negative. A skin biopsy revealed neutrophilic dermatosis compatible with Sweet s disease. The patient made a prompt recovery without the use of corticosteroids. Conclusion Because of its multisystem nature Sweet s syndrome may present diagnostic difficulty to specialists. Correct diagnosis by skin biopsy will prompt appropriate treatment. Introduction Sweet s syndrome is a multi-system neutrophilic disease first described by Dr. Robert Douglas Sweet in 1964 1 and is also known as acute neutrophilic dermatosis