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Báo cáo y học: " Carcinoid tumor of the verumontanum (colliculus seminalis) of the prostatic urethra with a coexisting prostatic adenocarcinoma: a case report"

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Carcinoid tumor of the verumontanum (colliculus seminalis) of the prostatic urethra with a coexisting prostatic adenocarcinoma: a case report | Smith et al. Journal of Medical Case Reports 2010 4 16 http www.jmedicalcasereports.eom content 4 1 16 jAc JOURNALOF medical ÌỤr case REPORTS CASE REPORT Open Access Carcinoid tumor of the verumontanum colliculus seminalis of the prostatic urethra with a coexisting prostatic adenocarcinoma a case report Maxwell Smith M Scott Lucia Priya N Werahera Francisco G La Rosa Abstract Introduction Urethral carcinoid tumors are very rare tumors with only four cases described in the literature. Case presentation We present the case of a 61-year-old man with a primary carcinoid tumor of the verumontanum colliculis seminalis portion of the prostatic urethra with a coexisting prostatic adenocarcinoma. In addition to whole mount hematoxylin and eosin staining special immunoperoxidase staining specific for chromogranin A neuron specific enolase synaptophysin pan-cytokeratin and PSA and a special combined staining for racemase a-methyl CoA antigen and p63 antigen were performed. A review of the literature is included. A single focus of invasive prostatic adenocarcinoma was identified in the periphery of the mid-left posterior quadrant of the prostate. Approximately 17 mm from this adenocarcinoma within the verumontanum of the prostatic urethra there was a 3 mm maximal dimension carcinoid tumor. Conclusion Based on different histological features and antigenic profiles we concluded that the two tumors were distinct. Introduction Carcinoid tumors of the urethra are exceedingly rare neoplasms with only four cases reported in the literature 1-4 . Given this small number their clinical presentation course and prognosis are difficult to elucidate. We report the first case of a primary carcinoid tumor within the verumontanum of the prostatic urethra in a 61 year-old man who underwent radical prostatectomy for adenocarcinoma of the prostate. We reviewed the literature for both primary carcinoid tumors of the urethra and for synchronous urethral carcinoid tumors and prostatic .