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Báo cáo y học: " Invasive pulmonary aspergillosis 10 years post bone marrow transplantation: a case report"

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Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Invasive pulmonary aspergillosis 10 years post bone marrow transplantation: a case report | Journal of Medical Case Reports BioMed Central Open Access Case report Invasive pulmonary aspergillosis 10 years post bone marrow transplantation a case report Rifat Rashid 1 and David W Denning2 Address faculty of Medicine and Human Sciences University of Manchester Wythenshawe Hospital Manchester UK and 2School of Medicine Education and Research Centre the University of Manchester Manchester UK Email Rifat Rashid - rifatrashid@hotmail.com David W Denning - DDenning@manchester.ac.uk Corresponding author Published 26 January 2009 Received 3 April 2008 Journal of Medical Case Reports 2009 3 26 doi 10.1186 1752-1947-3-26 Accepted 26 January 2009 This article is available from http www.jmedicalcasereports.com content 3 1 26 2009 Rashid and Denning licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http creativecommons.Org licenses by 2.0 which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract__ Introduction Invasive pulmonary aspergillosis is a leading cause of mortality and morbidity in bone marrow transplant recipients. Establishing the diagnosis remains a challenge for clinicians working in acute care setting. However prompt diagnosis and treatment can lead to favourable outcomes Case presentation We report a case of invasive aspergillosis occurring in a 39-year-old Caucasian female 10 years after an allogeneic haematopoietic bone marrow transplant and 5 years after stopping all immunosuppression. Possible risk factors include bronchiolitis obliterans and exposure to building dust for example handling her husband s dusty overalls . There are no similar case reports in the literature at this time. Conclusion High clinical suspicion especially in the setting of failure to respond to broadspectrum antibiotics should alert clinicians to the

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